我国先后出台一系列扶持农机发展的政策。2022年，农业农村部印发《“十四五”全国农业机械化发展规划》，促进农业机械化转型升级，加快全产业链农机装备研发与推广。2023年，农业农村部、国家发展改革委等部门联合发布《全国现代设施农业建设规划(2023—2030年)》，提出2025年和2030年设施种植机械化、畜牧养殖机械化以及水产养殖机械化率目标预期，并加大金融支持力度，推动智慧农机发展。这极大地激发了农民购置农机的积极性，有效促进了农机的更新换代和技术进步，推动农业生产效率全面提高。
转自：康龙化成Amination of Aminopyridines via η6‑Coordination Catalysis
JiajiaChen, Yunzhi Lin, Wen-Qiang Wu, Wei-Qiang Hu, Jingkai Xu, and Hang Shi*
Key Laboratory of Precise Synthesis ofFunctional Molecules of Zhejiang Province, School of Science, WestlakeUniversity, Hangzhou 310030 Zhejiang Province, China; Institute of NaturalSciences, Westlake Institute for Advanced Study, Hangzhou 310024 ZhejiangProvince, China;
—J. Am. Chem. Soc.,2024, 146, 22906−22912
Recommended by Rui Jin _ MC5
ABSTRACT: Pyridine,a widespread aromatic heterocycle, features asp2-hybridizednitrogen atom that can readily coordinate to metals, leading to distinctiveachievements in catalysis. In stark contrast, π-coordination of pyridine andderivatives with transition metals is notably scarce, and the involvement ofsuch activation mode in catalysis remains to be developed. Herein, we presentamination reactions of aminopyridines that leverages the reversible πcoordination with a ruthenium catalyst as the arenophilic π acid, rather than relying on theconventional κ-N coordination. Specifically, atransient η6-pyridine complex functions as theelectrophile in the nucleophilic aromatic substitution with amines, providing adiverse array of products via the cleavage of the pyridyl C−N bond. Inaddition, this method can be employed to incorporate chiral amines and 15N-labeled amines.
Background and This Work
Selected Examples of Catalytic Aminationof 2-Aminopyridines and Extended Applications
（转自：康龙化成）股票配资平台的认可
发布于：北京市